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The detailed (and as complete as possible) description of plausible or observable pathways leading from reactants to products of a chemical process. This tag should be applied to questions about these processes. It may be applied to hypothetical and/or proposed mechanisms.

7 votes
2 answers
3k views

Why does no Robinson Annulation occur after the Michael addition?

Under basic conditions a Michael addition reaction can be used to convert compound A into product C. Explain why no Robinson annulation cyclic product is observed? Compound A Product C …
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3 votes
1 answer
3k views

Synthesis of Pseudopelletierine, Mannich reaction base catalysed

The synthesis of Pseudopelletierine starts from glutardialdehyde, which reacts with methylamine and acetonedicarboxylic acid in a two-fold Mannich reaction. This is the reaction: I need to write t …
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4 votes
1 answer
1k views

Dehydration of secondary alcohol via E1 mechanism

Write the mechanism for this reaction: I am trying to do a dehydration of an alcohol using the reagents sulfuric acid and acetic acid. I don't know how I am supposed to use the acetic acid, instead …
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12 votes
2 answers
5k views

Bromination of 1,3,5-cyclooctatriene followed by nucleophilic substitution by excess dimethy...

Write the mechanism for the following reaction (bromination of 1,3,5-cyclooctatriene followed by nucleophilic substitution by excess dimethylamine): My answer so far: I have only shown one of the …
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