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Questions tagged [reaction-mechanism]

The detailed (and as complete as possible) description of plausible or observable pathways leading from reactants to products of a chemical process. This tag should be applied to questions about these processes. It may be applied to hypothetical and/or proposed mechanisms.

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Reaction of orthocresol with butyrolactone in presence of AlCl3 and heat

What will be the major product of the following reaction? Please also help me with the mechanism. I'm not sure whether C- acylation or O- acylation will occur here. And if O- acylation does occur, I ...
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1answer
38 views

Friedel-Craft reaction with amide substituent

In this question, I know that aniline will not undergo FC reaction as it forms a complex with $\ce {AlCl3}$ and precipitates out. The answer given is (c) and I agree with it. However, the benzene ring ...
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0answers
23 views

Oxidative Addition - Really concerted?

I guess you are all familiar with the oxidative addition or reductive elimination reaction in organometallic chemistry. If you read further into the topic you may find different pathways like via ...
3
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1answer
113 views

How does Grignard reagent form? [duplicate]

So I've read that during the formation of the Grignard reagent, The R-X bond cleaves homolytically forming free radicals. My question is how is this happeneing? Due to the high electronegativity ...
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1answer
306 views

ICHO Synthesis Problem 2018

I've several doubts about this ICHO synthesis problem, which was a part of the preparatory problem package of 2018 (so yes, it's not a part of an ongoing contest) Before sharing the answer given, I'...
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1answer
27 views

Can an iodine clock reaction work without using a strong acid?

I'm going to do an iodine clock reaction for a project and we had to submit the materials and safety sheets for the experiment a while ago. I thought I could do one by using hydrogen peroxide, sodium ...
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1answer
28 views

Rate of reaction [on hold]

If I recall correctly I was told that the rate of reaction approximately doubled for every 10 degree C rise in temperature. Is the a similar rule of thumb for increase in pressure. I am working on ...
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0answers
42 views

Disiamylborane on alkyl halides

I am having problem predicting the last product in the following reaction: $$\ce{CH#CH ->[Na/NH3 (l)][(Excess)] (P) ->[DCl] (Q) ->[(i)Sia2BH][(ii)CH3COOH] (R)}$$ I am getting an alkyl ...
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Favorskii rearrangment

Why does the alkoxide anion dont act as a nucleophile in the fevorskii rearrangement? It can displace halide as halide is alpha to carbonyl and carbonyl decreses the energy of c-halide lumo
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30 views

HELP organic chemistry reaction [on hold]

help I need the mechanism of this synthesis
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1answer
34 views

Acidic, Basic, and Neutral Medium

So I'm new to this concept and I can't find any proper explanation to this. What does it mean for a reaction to occur in an acidic, basic, or neutral medium?
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Major product for aldol condensation between acetophenone and acetaldehyde

Crossed aldol condensation is done between acetaldehyde and acetophenone by using NaOH as the base. So, here we can get 4 possible products. But which one would be the major? I know that acetaldehyde ...
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0answers
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Pool of fluid from batteries that my son sat in [closed]

My son (8) likes to create things and was messing around with some wires and a couple of alkaline D batteries. I think he was trying to connect them together. I heard some "thunks" and I think he ...
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0answers
28 views

Pyrimidine chemistry

Why C4 position in pyrimidine ring is more reactive then C2 position in nucleophilic aromatic substitution and Pd chemistry? Should not be the C2 position the most reactive because of the effect of ...
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1answer
35 views

Quaternary Ammonium salts and peroxy acid

I came across this question in my test: This compound is treated with $\ce{CH_3CH_2I}$ and then with $\ce{H_2SO_5}$ and heated. The product is: A) B) $\ce{CH_2CH_2}$ ...
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0answers
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I need help to explain the reaction of a dissolvable magnesium alloy to the masses (Reaction within) [closed]

We use a Magnesium based metal alloy in an application where when the alloy is exposed to water with a high salinity (Chlorides) it dissolves. The below chemical reaction was provided and we would ...
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1answer
84 views
+50

Reaction of urea and thiourea with nitrous acid

I was told that urea on reaction with nitrous acid gives nitrogen gas, carbon dioxide and water. While on the other hand, thiourea on reaction with nitrous acid gives $\ce{H+}$, thiocyanate ion and ...
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0answers
42 views

First Order Chemical Kinetics

I have the following system of reactions: \begin{align} M & \xrightarrow{\lambda(M,W)}M+M \\ W & \xrightarrow{\lambda(M,W)}W+W \\ M & \xrightarrow{\mu} \emptyset \\ W & \xrightarrow{\...
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1answer
45 views

A doubt on the action of NBS/CCl4

Suppose we have a alkene( ex- 2- butene) we try to subject it to allylic bromination using NBS/CCl4 and then the mixture is separated using fractional distillation. According to me as the reaction ...
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1answer
40 views

How to calculate the kinetic order of an enzymatic reaction?

This question is concerning the metabolism of ethanol by an alcohol dehydrogenase enzyme. Usually people metabolize alcohol equivalent to "one beer per hour". One beer is said to contain 33cL. The ...
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1answer
72 views

Can anyone tell me what reaction is this?

I came across this reaction, but I have no idea what reaction is this. Can anyone please tell me? What will be the products? My first guess is that a carbene will be formed which will attack on the ...
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0answers
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Mechanisms of Birch and Bouveault-Blanc Reductions

The question is all about the sequence of a possible Birch- and Bouvault-Blanc-Reduction in this exemplary substrate. With which reduction the mechanism begin? My first attempt was to classify the ...
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1answer
43 views

Does OH- attack carbonyl carbon in aldehyde during aldol reaction?

Why does $\ce {OH^-}$ not attack the carbonyl carbon in an aldehyde during the aldol reaction and instead, deprotonate the $\alpha$ hydrogen to form an enolate intermediate? Also, why does the ...
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0answers
28 views

Diels Alder stereoselectivity

I'm familiar with the endo rule as well as the regioselectivity of the reaction. However, what I fail to understand is the stereoselectivity of the product in relation to the diene. For example, in ...
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2answers
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Why isn't iron (III) oxide an effective catalyst for decomposing hydrogen peroxide?

I've been working on a project involving the catalyst iron(III) oxide for decomposing hydrogen peroxide. It barely seemed to produce any oxygen. https://www.youtube.com/watch?v=Ta4DomSDzF8 This video ...
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0answers
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Damage to the coating on polycarbonate lenses

Can infusions of Vancomycin cause a secretion through the skin that can damage the coating on polycarbonate lenses?
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0answers
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Reaction of 2-phenylpropanamide with (NaOH/Br2) [on hold]

Please explain why 1-phenylethan-1-amine is produced on reaction with $\ce{NaOH}$/$\ce{Br2}$, but 2-phenylpropanamine is produced due to reaction with $\ce{LiAlH4}$ in ether? I expected that 2-...
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0answers
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What is a probable mechanism for acid catalysed decarboxylation of alpha-hydroxy acid?

The following question was on one of the tests we had recently Now i worked out the intermediates and the product as follows: The first step is an intramolecular Cannizzaro reaction in which the ...
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0answers
55 views

Where will a H+ attack on 6-hydroxyhexan-2-one? [closed]

Where will a H+ attack on 6-hydroxyhexan-2-one? Protonation can take place either on the ketone or the alcohol. So where will it attack? In short, on which of the two oxygen atoms is electron density ...
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1answer
44 views

Friedel–Crafts with unsaturated halides

Which of the following compounds will not undergo Friedel–Crafts reaction with benzene: vinyl chloride or allyl chloride? According to me vinyl chloride will be a better electrophile than allyl ...
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0answers
53 views

Abnormal reaction of grignard reagent

My book states that: When isopropyl magnesium bromide is added to diisopropyl ketone, the expected tertiary alcohol is not obtained; instead the secondary alcohol; diisopropyl carbinol is obtained ...
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1answer
40 views

Can't decide between E1 and E2 mechanisms for this reaction

I can see that due to the substrate being bulky, an elimination reaction will take place and not substitution. The reagent is a strong base. E1 reactions are independent of the base chosen, and E2 ...
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0answers
35 views

Organic Chemistry - Reduction

Can anybody help me with the product? Seems like Birch reduction, but Birch reduction is used for conjugated systems and alkynes.
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How does the ease of oxidative addition vary with identity of X?

Recently I studied I Heck coupling reaction which starts with oxidative addition, and I've read that the reactivity of halogen in heck coupling is ordered in this way: $$\ce{X = I > Br > OTf &...
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1answer
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Clarification in the mechanism for Molisch's test for glucose

Wikipedia says Molisch's test is a sensitive chemical test, named after Austrian botanist Hans Molisch, for the presence of carbohydrates, based on the dehydration of the carbohydrate by sulfuric ...
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0answers
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Reactions Among Copper, Sulfuric Acid, and Nitric Acid Mixture

I'm trying to determine what reactions are occurring between a solution composed of 10 wt% $\ce{HNO3}$, 30 wt% $\ce{H2SO4}$ and the remainder $\ce{H2O}$ and a piece of pure copper metal. The solution'...
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1answer
71 views

Are nucleophilic aromatic substitutions stepwise or concerted?

Recently, there has been a lot of discussion about nucleophilic aromatic substitution (SNAr) reactions apparently being concerted instead of stepwise (e.g. Krämer, K. Textbook aromatic substitution ...
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1answer
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Question about reaction notation (commas, numbers, and dashes)

I'm learning Organic Chemistry and in my university course we're using commas, numbers, and dashes in the reactions. My question is: What is the difference between these 3 forms of notation? $$\ce{-...
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How i can make an animated organic reaction mechanism?

I'm wondering if there is a software that helps to make an animated organic mechanism and show how arrows go. It would be clearer in visualizations.
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1answer
48 views

Ozonolysis mechanism question

Is this mechanism will be similar to ozonolysis ? My try : My Question is will B be the answer ? And what does Me2S do ?
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1answer
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What is/are the product(s) of the reaction of (5,5-²H₂)cyclopenta-1,3 diene with NaH, and quenched with H₂O?

$\ce{NaH}$ breaks as $\ce{Na+}$ and $\ce{H-}$. Here $\ce{H-}$ acts as a nucleophile and attacks at a place where the electron density is less. But the $\ce{C-D}$ bond is stronger than the $\ce{C-H}$ ...
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1answer
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Why are reactions with higher activation energy more sensitive to temperature?

In the above picture it is stated clearly, with an example, that the more the Ea of a rxn the more it's sensitive to temperature, and hence even a small change in temperature in a reaction with high ...
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0answers
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Reaction of NaI + Acetone with Di Halides

I was studying about methods of creating alkynes from Di halides. One of the methods used is adding $\ce{NaI}$ $\ce{+Acetone}$.There's no mechanism given. $\ce{NaI}$ $\ce{+Acetone}$ is also used in ...
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1answer
64 views

Which reaction rate formula is suited for diatomic molecules in a plasma?

I am an experimental physicist, so I unfortunately do not know much about chemistry except the basics. For my current study, I am investigating diatomic molecule formation in plasma. These diatomic ...
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1answer
91 views

hydrogenation using H2 + Ni2B [closed]

I am having trouble understanding why hydrogenation with $\ce{Ni2B}$ gives anti-addition. all my book says is this: Could someone explain the mechanism.
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31 views

Question related to KMnO4

Why in acidic medium $\ce{KMnO4}$ oxidizes $\ce{KI}$ ($\ce{I-}$) to $\ce{I2}$ but in alkaline medium to $\ce{IO3-}$? $\ce{KMnO4}$ is a stronger oxidising agent in acidic medium then why doesn't it ...
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1answer
73 views

Most reactive site for electrophilic aromatic substitution

I was given a problem in which I had to identify the most reactive site for electrophilic substitution out of the positions 1,2,3,4 (shown in the figure). My Approach: Upon drawing the resonating ...
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0answers
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What is the purpose of tetrazole in oligonucleotide synthesis?

The ATDBio book on nucleic acids describes tetrazole as an activator required to couple nucleotides. The diisopropylamino group of the nucleoside phosphoramidite is protonated by the activator, ...
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1answer
113 views

Reaction between HCl and NaHCO3 [duplicate]

I want to know why in the reaction between HCl and NaHCO3, we have CO2 and H2O instead of H2CO3 ?
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1answer
75 views

Why do nonmetal oxides react with water to form acidic compounds? [closed]

I am confused about the molecular basis by which nonmetal oxides react with water to form acidic compounds. For example, I understand that sulfur trioxide reacts with water to form sulfuric acid as ...