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Confusedbyeverything
Confusedbyeverything
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I can not understand why a peroxide $\ce{R-O-O-R}$ is considered reactive and unstable.

Going down one row on the periodic table, a disulfide bridge ($\ce{R-S-S-R}$) is apparently super stable and super important to proteins 3d structure.

At the same time, a thioester is considered to be as unstable/reactive as ATP and the ester is the stable one?

What am I conceptually missing here to explain this contradiction?What am I conceptually missing here to explain this contradiction?

I can not understand why a peroxide $\ce{R-O-O-R}$ is considered reactive and unstable.

Going down one row on the periodic table, a disulfide bridge ($\ce{R-S-S-R}$) is apparently super stable and super important to proteins 3d structure.

At the same time, a thioester is considered to be as unstable/reactive as ATP and the ester is the stable one?

What am I conceptually missing here to explain this contradiction?

I can not understand why a peroxide $\ce{R-O-O-R}$ is considered reactive and unstable.

Going down one row on the periodic table, a disulfide bridge ($\ce{R-S-S-R}$) is apparently super stable and super important to proteins 3d structure.

At the same time, a thioester is considered to be as unstable/reactive as ATP and the ester is the stable one?

What am I conceptually missing here to explain this contradiction?

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jerepierre
jerepierre
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Why are peroxides unstable, but disulfide brigesbridges considered stable, while esters? Why are esters stable but thiolesters are unstable?

I can not understand why a peroxide R--O--O--R$\ce{R-O-O-R}$ is considered reactive and unstable.

Going down one row on the PT we getperiodic table, a disulfide bridge: R--S--S--R which ($\ce{R-S-S-R}$) is apparently super stable and super important to proteins 3d structure.

BUT....

At the same time, a thioester is considered to be as unstable/reactive as ATP and the ester is the stable one?

whatWhat am I conceptually missing here to explain this contradiction?

Why are peroxides unstable, but disulfide briges considered stable, while esters are stable but thiolesters are unstable?

I can not understand why a peroxide R--O--O--R is considered reactive and unstable.

Going down one row on the PT we get a disulfide bridge: R--S--S--R which is apparently super stable and super important to proteins 3d structure.

BUT....

a thioester is considered to be as unstable/reactive as ATP and the ester is the stable one?

what am I conceptually missing here to explain this contradiction?

Why are peroxides unstable but disulfide bridges considered stable? Why are esters stable but thiolesters are unstable?

I can not understand why a peroxide $\ce{R-O-O-R}$ is considered reactive and unstable.

Going down one row on the periodic table, a disulfide bridge ($\ce{R-S-S-R}$) is apparently super stable and super important to proteins 3d structure.

At the same time, a thioester is considered to be as unstable/reactive as ATP and the ester is the stable one?

What am I conceptually missing here to explain this contradiction?

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Mithoron
Mithoron
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I can not understand WHYwhy a peroxide R--O--O--R is considered reactive and unstable.

goingGoing down one row on the PT we get a disulfide bridge: R--S--S--R which is apparently super stable and super important to proteins 3d structure.

BUT....

a thiolesterthioester is considered to be as unstable/reactive as ATP and the ester is the stable one ?????????

what am I conceptually missing here to explain this contradiction  ?

I can not understand WHY a peroxide R--O--O--R is considered reactive and unstable

going down one row on the PT we get a disulfide bridge: R--S--S--R which is apparently super stable and super important to proteins 3d structure.

BUT....

a thiolester is considered to be as unstable/reactive as ATP and the ester is the stable one ?????????

what am I conceptually missing here to explain this contradiction  ?

I can not understand why a peroxide R--O--O--R is considered reactive and unstable.

Going down one row on the PT we get a disulfide bridge: R--S--S--R which is apparently super stable and super important to proteins 3d structure.

BUT....

a thioester is considered to be as unstable/reactive as ATP and the ester is the stable one?

what am I conceptually missing here to explain this contradiction?

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Confusedbyeverything
Confusedbyeverything
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