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For questions about reactions that favour the formation of one or more stereoisomers.

4 votes

Effect of protecting group on diastereoselectivity of LiAlH4 reduction of α-hydroxyketones

The $\ce{TBDPS}$ group (tert-butyldiphenylsilyl) is a very bulky protecting group. A silicon atom is bonded to the oxygen, which already acts as a larger carbon atom. That is then substituted by three …
orthocresol's user avatar
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1 vote

How to Predict the Formation of Racemic Mixtures or Single Products from a Diels Alder React...

It is very simple: if you do not have any enantiopure compound present at the beginning of the reaction, the end product will either be inherently symmetric (contain a plane of centre of symmetry) or …
Jan's user avatar
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