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For questions involving the nucleophilicity of a chemical species. Not to be confused with "basicity", use the [acid-base] tag instead.

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Selectivity in tosylation of sulphur and oxygen

Problem Answer Question The first step involves a nucleophilic substitution on the sulphur atom of the tosyl group. I reasoned that in the cyclohexane substrate, the sulphur atom (thiol group) wil …
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