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This tag should be applied to questions about mechanisms, selectivity, or other aspects of aldol reactions.

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Why is the reverse aldol cleavage of fructose 1,6-bisphosphate highly endergonic under stand...

I have another question similar to this one. I just don't have intuition for why reactions are thermodynamically favorable or unfavorable and I'd like to build it. This time I'd like to ask about th …