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changed "opening" to "closure".
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user55119
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Stereoselectivity of ring openingclosure in intramolecular iodolactonisation

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orthocresol
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Iodolactonization stereoselectivity Stereoselectivity of ring opening in intramolecular iodolactonisation

Question

Iodolactonisation of tert-butyl octa-1,7-dien-4-yl carbonate

What is the product of the reaction above?

The options in which I haveam mainly confused between the doubt arefollowing two options:

(A) Option A

or (B) Option B

Possible answers

So howHow do we decide whether that $\ce{CH_2-I}$ group will come outside the plane or go insideresulting stereochemistry of the plane$\ce{CH_2I}$ group?

The answer given is the one in which $\ce{CH_2-I}$ is going outsidecoming out of the plane, i.e. (a).

Iodolactonization stereoselectivity

Question

What is the product of the reaction above?

The options in which I have the doubt are:

(A) Option A

or (B) Option B

So how do we decide whether that $\ce{CH_2-I}$ group will come outside the plane or go inside the plane?

The answer given is the one in which $\ce{CH_2-I}$ is going outside the plane.

Stereoselectivity of ring opening in intramolecular iodolactonisation

Iodolactonisation of tert-butyl octa-1,7-dien-4-yl carbonate

What is the product of the reaction above?

I am mainly confused between the following two options:

Possible answers

How do we decide the resulting stereochemistry of the $\ce{CH_2I}$ group?

The answer given is the one in which $\ce{CH_2-I}$ is coming out of the plane, i.e. (a).

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Mithoron
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Will it go inside the plane or come outside the plane? Iodolactonization stereoselectivity

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Aniruddha Deb
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V.G
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V.G
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