Timeline for Role of Cu in Corey-House synthesis
Current License: CC BY-SA 4.0
12 events
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| Oct 22, 2018 at 13:23 | history | edited | SendersReagent | CC BY-SA 4.0 |
Fixing links (again)
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| Apr 13, 2017 at 12:57 | history | edited | CommunityBot |
replaced http://chemistry.stackexchange.com/ with https://chemistry.stackexchange.com/
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| Mar 8, 2016 at 15:59 | vote | accept | Shodai | ||
| Mar 7, 2016 at 22:37 | history | edited | Mithoron | CC BY-SA 3.0 |
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| Mar 7, 2016 at 19:41 | comment | added | SendersReagent | I've updated my answer to include a link to another Chemistry.SE answer about lithium-halogen exchange. | |
| Mar 7, 2016 at 19:34 | history | edited | SendersReagent | CC BY-SA 3.0 |
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| Mar 7, 2016 at 16:25 | comment | added | SendersReagent | The Li-X exchange mechanism isn't really known for sure yet. This presentation from the MacMillan group talks about three proposed mechanisms: radical exchange, nucleophilic attack on the halogen, and a four-centered intermediate. I would guess it doesn't undergo normal nucleophilic attack due to hard-soft acid-base chemistry, i.e. poor orbital overlap. I'm not totally sure, though. | |
| Mar 7, 2016 at 8:40 | comment | added | Shodai | I see, that helps, but why does RLi undergo that reaction? Isn't R-Li a strongly polarized bond? What kind of bond is it actually? And what reaction is this undergoing? | |
| Mar 6, 2016 at 11:49 | history | edited | SendersReagent | CC BY-SA 3.0 |
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| Mar 6, 2016 at 5:00 | history | edited | SendersReagent | CC BY-SA 3.0 |
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| Mar 5, 2016 at 22:47 | history | edited | SendersReagent | CC BY-SA 3.0 |
Update, typos
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| Mar 5, 2016 at 17:56 | history | answered | SendersReagent | CC BY-SA 3.0 |