Timeline for Acidity of thiamine - how comes hydroxide anion with pK about 15 ionizes thiamine with pK about 18?
Current License: CC BY-SA 4.0
5 events
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Aug 18, 2020 at 22:02 | history | edited | Rafael L | CC BY-SA 4.0 |
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Aug 18, 2020 at 22:02 | comment | added | Rafael L | I see that a carbene can be formed, but he specifically said "will produce a resonance stabilized carbanion", which does not seem to be the case | |
Aug 15, 2020 at 21:56 | history | edited | Mathew Mahindaratne | CC BY-SA 4.0 |
Edited to improve formatting and clarity.
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Aug 15, 2020 at 20:46 | comment | added | Mithoron | Your second point is good, but first is incorrect - formal charge on carbon is only in mesomeric structure with dipolar bond, there's another one - carbenic. | |
Aug 15, 2020 at 5:30 | history | answered | Rafael L | CC BY-SA 4.0 |