Timeline for Why is it aqueous and ethanolic conditions for nucleophillc substitution of cyanide ion with benzyl chloride?
Current License: CC BY-SA 4.0
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| Apr 27, 2019 at 10:23 | comment | added | Raoul Kessels | No, it is not required. Apolar solvents are fine. In this case it is just a point of solubility. Note that the most polar reagent is the cyanide anion (and it's counter ion). The reaction itself is an Sn2, so not much polar stabilization is required. What is needed is to join the two reagents, either by choosing a solvent in which both are soluble or getting the cyanide in the solvent with a phase transfer catalyst | |
| Apr 26, 2019 at 21:33 | comment | added | daniel | More broadly speaking do reactions involving haloalkanes or halogen functional groups require alcoohlic conditions as the h-x bond is polar? | |
| Apr 26, 2019 at 8:08 | history | answered | Raoul Kessels | CC BY-SA 4.0 |