Timeline for Determining R and S configuration for a cyclic compound when the lowest priority group is on the plane of the paper
Current License: CC BY-SA 4.0
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Oct 5, 2018 at 14:15 | comment | added | Organic Chemistry Explained | Yes, I shouldn't have been so hasty in saying there's only two ways to do this! Swapping two substituents always inverts the configuration (eg. S -> R), so doing one swap, followed by a second swap gets back to the original configuration (eg. S -> R -> S). So, rather than rotating like I did in (2), you could draw out the chiral centre with 1, 2, 3, 4, then do two sequential swaps that end up putting the lowest priority group going away from you (ie. with the hashed bond). | |
Oct 5, 2018 at 13:56 | comment | added | AussieKenDoll | Thanks! Is it possible to use the swap method for this cyclic compound? If yes, Do I only need to consider the molecules which I gave the priority (1,2,3,4) when doing molecule swap method to determine the R and S configuration of the above compound(4th priority on the plane of the paper)? | |
Oct 5, 2018 at 13:40 | review | First posts | |||
Oct 5, 2018 at 14:20 | |||||
Oct 5, 2018 at 13:38 | history | answered | Organic Chemistry Explained | CC BY-SA 4.0 |