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chemrese
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4 votes
1 answer
340 views

Role of NaI in Formation of Silyl Enol Ethers using Chloro(trimethyl)silane

4 votes
2 answers
273 views

LiOH hydrolysis of methyl 2,2-dimethoxyacetate not giving product?

3 votes
0 answers
200 views

what's the mechanism of formation of succinimide ester?

3 votes
1 answer
212 views

hydroxychloroquine (HCQ) Synthesis: Which mechanism?

3 votes
1 answer
233 views

I am seeing Doublet of Doublets peaks when I should see just a doublet

2 votes
1 answer
426 views

Benzyl Carbocation Stability: Would electron-withdrawing group on the ring destabilize the carbocation?

2 votes
1 answer
208 views

DCC coupling of N-hydroxysuccinimide and 2,2-dimethoxyacetic acid

2 votes
1 answer
385 views

Can ring inversion in Cis-Decalin allow the E2 reaction?

2 votes
0 answers
60 views

Isolable activated esters: Other than N-Hydroxysuccinimidyl ester and Pentafluorophenyl ester?

1 vote
1 answer
179 views

What does it mean by 'the residue was taken up in solvent' in synthesis protocol?

1 vote
0 answers
644 views

How to remove Acetic Anhydride?

1 vote
2 answers
106 views

Sonication to purify solid product- the crude product just disappeared

0 votes
0 answers
75 views

Struggling to make SMCC

0 votes
0 answers
150 views

Do aprotic solvents "slow down" SN1 reactions?

0 votes
0 answers
64 views

What's the purpose of stirring the mixture at 0 degree and dding NaOH to the organic reaction mixture?

0 votes
0 answers
247 views

A broad singlet at 2.27 ppm?

0 votes
0 answers
69 views

Aldol Reaction in Water Not Working

-2 votes
1 answer
20 views

silyl ketene acetal vs Benzene, which compound has a higher nucleophilicity? [closed]