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3

Now a days, sulfonephthaleins can be prepared by reaction of readily available saccharin and the desired plenol compound (Ref.1 & Ref.2). In this method, active reagent, sulfobenzoic anhydride will be prepared in situ as depicted in following diagram: In this method, it's described the preparation of phenolsulfonephthalein (Phenol Red). If you use ...


2

Aluminium iodide ($\ce{AlI3}$) is first introduced in 1984 as an easily accessible, a highly regioselective versatile ether-cleaving reagent with novel cleavage pattern (Ref.1). Application of $\ce{AlI3}$ in organic synthesis has been reviewed (Ref.2) and it seems like acetonitrile is the best solvent to be used in catechol ether demethylation (e.g., 2-...


1

o-Sulfobenzoic Anhydride is prepared by cyclisation of ammonium o-sulfobenzoate (itself prepared by cHCl hydrolysis of saccharin) with thionyl chloride in benzene. The Organic Syntheses procedure is here: Org Syn


1

It has been observed spectroscopically but has not been isolated as a pure substance. Thiocyanic_acid Regarding the sodium salt, creating it in concentrated sulphuric acid cannot be considered seriously. $\ce{P4O10}$ would not be much better, forming various forms of condensated phosphoric acid. Furthermore, carbon dioxide manifests weak oxidative ...


3

Yes, it is possible. The Rosenmun-von Braun reaction is the classic method of doing this. But it involves CuCN which is quite toxic. I'd suggest that you investigate some more modern methods. These use palladium based catalysts. Many also use Zn(CN)2 which is still toxic but less so than CuCN. These two are good for starters: Iqbal, Z., Lyubimtsev, A.,...


1

Note that the first reaction would require substantial amount of heat to assure the designated product $\ce{NaAlO2}$ is formed (nowhere near STP): $$\ce{2 Al(s) + 2 NaOH(l) + 2 H2O(g) ->[\pu{\approx 450 °C}] 2 NaAlO2(s) + 3 H2(g)}$$ In aqueous solution the product would be tetrahydroxoaluminate $\ce{[Al(OH)4]-}:$ $$\ce{2 Al(s) + 2 NaOH(aq, conc) + 6 ...


0

Here is a possibly interesting safe path to try for a Zinc (or Aluminum) Hg amalgam, which can be used in organic synthesis (e.g., for the Clemmensen reduction) courtesy of the field of Hydrometallurgy. It starts by first placing a sheet of, say, pure Zinc in HCl to create some surface absorbed H atoms (or Al in NaOH, where purity is important to avoid toxic ...


5

Nicco: Of course you can't "see it". If you were given the correct structure, the solution to your post would be straightforward. There should be a double bond in the lactam ring as shown in compound 1. The reaction is conducted in acetonitrile (bp. 82oC) at reflux. These conditions allow for a Claisen rearrangement to occur to form ketolactam 2. Subsequent ...


2

You probably did get your anticipated reaction, but unlike carbon dioxide or hydrogen ammonia is highly soluble in water. Unless your reactants are more highly concentrated than is possible with the limited solubility of calcium hydroxide, the ammonia remains in solution instead of giving off bubbles or a smell. There are variuos ways to render this ...


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