# Tag Info

1 vote

### What can I do if I don't get a phase separation between my organic and water phases?

An additional option besides adding salt and having patience, is to place your funnel inside a heating oven at a temperature that is not harmful to your reaction. In my experience, it helped with the ...
• 546
Accepted

### How to synthesize 1,1,1-trichloro-2,4-dimethylpentan-2-ol from methyl isobutyl ketone?

Chloroform anion generated with powdered KOH reacts with ketones to give addition resulting in the trichloromethyl methyl carbinol as reported by Willgerodt in 1881 (Chem. Berichte vol 14 245-60) as ...
• 18.2k
Accepted

### How does coenzyme A produce proton from pyruvate ions?

The reversible conversion of pyruvate ion and coenzyme A (CoA) into $\ce{acetyl-CoA}$ and formate ion (Figure 1) is not a one step reaction but a complex multistep radical reaction (Ref.1), thus it is ...
• 34.6k
1 vote

### Information about liquefied carbon factories from carbon dioxide

If you compress a gas in a syringe at $20°$C, its temperature increases a bit (say $+ 10$ °C). If you now maintain the pressure and let the compressed gas cool down, its temperature goes slowly back ...
• 20.6k

### Information about liquefied carbon factories from carbon dioxide

I think you mean dry ice; solid carbon dioxide, not carbon. It is made very cold and freezes. At atmospheric pressure carbon dioxide sublimes, no liquid; gas to solid. Look up a CO2 phase diagram. Not ...
• 2,942

### The major product of radical halogenation: Why is it a halogen attached to a primary carbon and not a tertiary carbon in the given example?

The experimental relative rates of chlorination to primary, secondary, and tertiary positions are $1$, $3.8$, and $5$, respectively. In the given compound $\ce{(CH3)3CH}$, there are $9$ identical ...
• 1,135
1 vote

### Substitution v/s elimination

I think both elimination and substitution reaction will occur any of them can dominate cos ethoxide ion is a strong nucleophile and in presence of a alcohol as a solvent. So the reaction which will ...
• 193
Accepted

### Reaction of 2-carboxybenzaldehyde with $\ce{NaCN/HCl}$ - does carboxylic acid interfere?

@Waylander's suggestion that 3-cyanophthalide [3-oxo-1,3-dihydroisobenzofuran-1-carbonitrile] 6 is expected as the product of the reaction is well-reasoned. This reaction has been reported by Hesse, ...
• 13.3k
Accepted

### Converting benzaldehyde to benzophenone in no more than two steps

I could give you a satisfactory answer, but I don't say that this is the best method. Conversion of benzaldehyde to benzoyl chloride:You can achieve this by adding $\ce{Cl2}$ or $\ce{SO2Cl2}$ (or ...
• 1,135
1 vote

### Reactivity of 1-bromo-4-tert-butylcyclohexane isomers with methanol

You are right on the part of E2, 2 will react slower. The reactivity of SN1 follows the same order - the carbocations are same but in 1 due to $\ce{Br}$ being on the axial position, the $\ce{C-Br}$ ...
1 vote

### Temperature required for E1 elimination reaction

This is a question that is answered by careful experimentation [Possibly the experiment has been done already]. Primary and secondary require high T to dehydrate usually about 150-200C, intermediate ...
• 635
Accepted

• 26.6k

### Systematic and preferred names of acetamide

The first thing to do when constructing a systematic name is to find the parent structure - be it a cycle, or in this case an acyclic chain. You choose the parent structure with the most skeletal ...
• 1,879
Accepted

### Is RCOOH + H2SO4 + heat a viable alternative to RCOCl + AlCl3 in Friedel-Crafts acylation?

Sure it is possible. It is best known for intramolecular cyclisation using Polyphosphoric Acid (PPA) or Methanesulfonic acid more here. Examples are known of intermolecular Friedel-Craft acylation ...
• 18.2k