Questions tagged [synthesis-golf]

Synthesis golf is a community initiative to encourage active participation on chemistry.SE by providing frequent synthetic challenges. Specific targets will be posted and users are encouraged to provide their synthetic routes, bounties are awarded to further encourage users to get involved.

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23
votes
1answer
266 views

Synthesis Golf X: TAK-457

I shall try to revive this! A full FAQ post has been written on chemistry.meta.SE, explaining the premise of synthesis golf and the 'rules'. Please take a look at this before answering (if you haven't ...
16
votes
3answers
577 views

Synthesis Golf IX: Tezacaftor

A full FAQ post has been written on meta.chem.SE, explaining the premise of synthesis golf and the 'rules'. Please take a look at this before answering (if you haven't already). The target of this ...
13
votes
2answers
339 views

Synthesis Golf VIII: 4,6-Diacetylhygrophorone A12

As usual we are a bit late on this, but here is this month's molecule: which is known as (4​R,5​S,6​R)-4,6-diacetylhygrophorone A12, and is an antifungal natural product isolated from mushrooms of ...
14
votes
1answer
336 views

Synthesis Golf VII: (+)-Clopidogrel

(+)-Clopidogrel (sold as Plavix) is a common pharmaceutical used to help combat the risk of heart disease. The World Health Organisation lists Plavix on its list of 'essential medicines' due to its ...
21
votes
3answers
522 views

Synthesis Golf VI: Muscarine

October's synthesis golf is rather late - apologies. I've chosen a slightly different-looking target this round, with the aim of inspiring a wider variety of routes. Muscarine is a natural product ...
15
votes
3answers
280 views

Synthesis Golf V: Denopamine

A full FAQ post has been written on meta.chem.SE, explaining the premise of synthesis golf and the 'rules'. Please take a look at this before answering (if you haven't already). This fifth round of ...
18
votes
2answers
444 views

Synthesis Golf IV: Plaunotol

A full FAQ post has been written on meta.chem.SE, explaining the premise of synthesis golf and the 'rules'. Please take a look at this before answering (if you haven't already). This fourth round of ...
19
votes
7answers
3k views

Synthesis Golf III: Chloramphenicol

A full FAQ post has been written on meta.chem.SE, explaining the premise of synthesis golf and the 'rules'. Please take a look at this before answering (if you haven't already). This third round of ...
31
votes
4answers
1k views

Synthesis Golf II: Erythronolide B

A full FAQ post has been written on meta.chem.SE, explaining the premise of synthesis golf and the 'rules'. Please take a look at this if you haven't already. This round of synthesis golf concerns ...
31
votes
6answers
1k views

Synthesis Golf I: Sodium Fluvastatin

A full FAQ exists on meta.chem.SE explaining the premise of synthesis golf, why we're doing this, and the ground rules. Please read this before posting an answer. The target for this first round of ...