# Questions tagged [henderson-hasselbalch-equation]

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### Sodium Citrate / Sodium Phosphate Buffer Calculations

I'm trying to work through the calculations of a specific paper (linked here / below) but, my numbers are way off and I can't get them to match for the life of me. I need to make the same buffer but ...
1 vote
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### Henderson-Hasselbalch equation and degree of dissociation

Is it possible to evaluate the degree of dissociation in unbuffered solutions, through the Henderson-Hasselbalch equation? For example: place acetic acid in a sodium hydroxide solution. After the ...
38 views

### Which pKa should I use in this Henderson/Hasselbalch rearrangement?

I have a question about the following formula: $$Mu/Pu = \frac{1+10^{pHm - pKa}}{1+10^{pHp- pKa}}$$ This formula can be found in the following paper: Begg, E. J., & Atkinson, H. C. (1993). ...
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### Measuring [A-]/[HA-] with Buffer and Indicator

I'm very confused on how to calculate the [A-]/[HA] value, given the fact that my dilution series uses buffers at various pH values with the same indicator (supplied at the same concentration to each ...
707 views

### How to calculate a citric acid and trisodium citrate buffer?

I am trying to calculate how to prepare 500 mL of a citric acid (H3Cit) and trisodium citrate (Na3Cit) buffer with a pH = 4.5 and a total concentration of 0.1 M. I know that it is necessary to use the ...
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### Slope ≠ 1 in Henderson-Hasselbalch graph for determination of pKa

The $\mathrm{p}K_\mathrm{a}$ of indicators can be determined via plotting a graph of $\log \left(\frac{\ce{In-}}{\ce{HIn}}\right)$ vs $\mathrm{pH}$ with the help of a spectrophotometer, from the ...
1 vote
310 views

### Henderson-Hasselbalch approximation

The Henderson-Hasselbalch approximation gives us a method to approximate the pH of a buffer solution. The basic equation is as follows: \mathrm{pH} \approx \mathrm{p}K_\mathrm{a} + \log\dfrac{\ce{[A^...