# Questions tagged [henderson-hasselbalch-equation]

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### Sodium Citrate / Sodium Phosphate Buffer Calculations

I'm trying to work through the calculations of a specific paper (linked here / below) but, my numbers are way off and I can't get them to match for the life of me. I need to make the same buffer but ...
1 vote
127 views

### Henderson-Hasselbalch equation and degree of dissociation

Is it possible to evaluate the degree of dissociation in unbuffered solutions, through the Henderson-Hasselbalch equation? For example: place acetic acid in a sodium hydroxide solution. After the ...
• 127
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### Which pKa should I use in this Henderson/Hasselbalch rearrangement?

I have a question about the following formula: $$Mu/Pu = \frac{1+10^{pHm - pKa}}{1+10^{pHp- pKa}}$$ This formula can be found in the following paper: Begg, E. J., & Atkinson, H. C. (1993). ...
• 29
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### Measuring [A-]/[HA-] with Buffer and Indicator

I'm very confused on how to calculate the [A-]/[HA] value, given the fact that my dilution series uses buffers at various pH values with the same indicator (supplied at the same concentration to each ...
707 views

### How to calculate a citric acid and trisodium citrate buffer?

I am trying to calculate how to prepare 500 mL of a citric acid (H3Cit) and trisodium citrate (Na3Cit) buffer with a pH = 4.5 and a total concentration of 0.1 M. I know that it is necessary to use the ...
1k views

### Slope ≠ 1 in Henderson-Hasselbalch graph for determination of pKa

The $\mathrm{p}K_\mathrm{a}$ of indicators can be determined via plotting a graph of $\log \left(\frac{\ce{In-}}{\ce{HIn}}\right)$ vs $\mathrm{pH}$ with the help of a spectrophotometer, from the ...
• 21
1 vote
310 views

### Henderson-Hasselbalch approximation

The Henderson-Hasselbalch approximation gives us a method to approximate the pH of a buffer solution. The basic equation is as follows: \mathrm{pH} \approx \mathrm{p}K_\mathrm{a} + \log\dfrac{\ce{[A^...
• 303
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### Derivation of Henderson–Hasselbalch equation

While deriving the Henderson–Hasselbalch equation why don't we consider the hydrolysis reaction? For example if we consider an acidic buffer of acetic acid and sodium acetate, why do we not consider ...
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