Questions tagged [aldol-reaction]
This tag should be applied to questions about mechanisms, selectivity, or other aspects of aldol reactions.
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Regioselectivity in Claisen condensation and aldol reaction
I'm having a hard time determining regio-selectivity in those two reactions.
At the image above I've drawn one example for each on of them. My question is how do we choose where the deprotonation ...
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What does the intramolecular aldol condensation of 6-oxoheptanal form?
I know that when 6-oxoheptanal is treated with NaOH, an intramolecular aldol condensation will take place. But will a five-membered ring or seven-membered ring be formed?
I know that the five-...
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Selectivity in aldol condensation between pivaldehyde and acetone
In a crossed aldol condensation (condensation between aldehyde and a ketone), the primary products are such, that the carbonyl group of the ketone remains intact, and the $\alpha$-hydrogen of ketone ...
- 6,765
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Base-promoted rearrangement of β-ketoester
Propose a reasonable mechanism for the following transformation:
I guess an enolate probably forms first, but then what does it attack to give something like the product in the question?
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P2NP synthesis ammonium acetate catalyst?
I am going to try to prepare some P2NP from benzaldehyde and nitroethane following this procedure:
The aldehyde (5g), 5 ml. of the nitroalkane, and 2g of ammonium acetate were added to 20 ml of ...
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Which Alpha-H will be extracted in intramolecular condensation rxn between ester and ketone
In this problem, which hydrogen will be extracted - the one near the ketone group (Marked 2) or the one near the ester (Marked 1)?
My approach:- In intramolecular reactions between aldehydes and ...
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