# What is a simple ratio in which atoms combine?

According to Modern Atomic Theory:

The ratio in which the different atoms combine may be fixed and integral but may not always be simple.

The example given is that in sugar molecule the ratio of $\ce{C,H}$ and $\ce{O}$ atoms is $12:22:11$ which is not simple.

Well, what I see here is that 12,22 and 11 are whole numbers, then why is this not a simple ratio?

Hemoglobin is $\ce{C2952H4664O832N812S8Fe4}$. Every high molecular weight Kraton thermoplastic elastomer triblock polymer contains a single atom of silicon at its exact middle. Plasma-drawn Spectra ultra-high molecular weight gel-crystallized polyethylene, some 20 times by weight stronger than steel cable, is $\ce{CH2}$.
Dicoronylene: $\ce{C48H20}$
Bacitracin: $\ce{C66H103N17O16S}$