While working with chiral molecule, we have pyridine in our reaction mixture. Molecule has four chiral centre and protection group-diacetal and acetyl groups which may break in harsh conditions. Please suggest work up methods to remove pyridine.
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$\begingroup$ Please, provide name/structure of the compound. As a general idea, I think pyridine might be evaporated given enough time, but it definitely is not fast or easy. $\endgroup$– permeakraOct 27, 2017 at 6:26
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2$\begingroup$ Aquaeous extraction with a saturated ammonium chloride solution is usually the way to go. $\endgroup$– JanOct 27, 2017 at 8:05
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1 Answer
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Extract the organic soln of the product with dilute aq. Cu(II) until the characteristic blue of the Cu-pyridine complex is absent from the aq. phase.
