I'm working on preparing SBF in my school's lab however a couple of components are missing which are $\ce{NaHCO3}$ (0.350 g) and $\ce{K2HPO4}$ (0.228 g) . Is it possible to replace these components with $\ce{NaCO3}$ and $\ce{KH2PO4}$ ?

The following link has the ions concentration of SBF:


I'm not a chemist and I would really appreciate your view on this.

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    $\begingroup$ No. Or rather, you can do that, but your pH will be way off. $\endgroup$ – Ivan Neretin Jul 6 '17 at 7:57
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    $\begingroup$ Probably not, sodium carbonate vs sodium bicarbonate are quite different (likewise for the phosphorous containing compounds). It looks like its setting up some kind of buffer, so changing things won't really work. You could just try it but all of the chemicals listed are really, really inexpensive and readily available- just buy what you need $\endgroup$ – NotEvans. Jul 6 '17 at 7:59
  • $\begingroup$ @NotEvans. Thanks...Is there another way to prepare SBF without the chemicals I'm missing? Another recipe :)? $\endgroup$ – Rawana Haso Jul 6 '17 at 13:43
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    $\begingroup$ I couldn't say, its very much not my area of chemistry. Google is likely your best bet (but as I say, just buy new chemicals, they're cheap... $\ce{NaHCO3}$ especially, you can find it in the baking aisle of your local supermarket... $\endgroup$ – NotEvans. Jul 6 '17 at 13:47

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