# How to convert glucose to fructose

How to convert glucose to fructose? Moreover, can there be direct conversion(not necessarily in a single step), or we have to use indirect means, such as from sucrose, or other higher carbohydrates, and then separating fructose from the products?

• This conversion is done enzymatically on industrial scale using "glucose isomerase". – ssavec Dec 16 '13 at 16:11
• thank you! are there any other methods, more 'chemical' in nature? – Shubham Dec 16 '13 at 17:06
• Probably yes, but in general, all sugar chemistry is nasty, as the -OH groups are very similar and it is difficult to perform efficient synthesis. And impossible to do simple synthesis. – ssavec Dec 17 '13 at 6:52

Below by that process we can convert from glucose to fructose. At first a mixture of glucose and excess phenyl hydrazene is heated, so glucose will form osazone. Then if we will give $$\ce{Zn}$$ and acetic acid with this, fructose will form.