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I am trying to perform an experiment in order to determine the efficiency of different antacids. An online search later shows that you add an HCl solution in a solution created with a base/antacid. However, the substances do not dissolve in water and hence precipitate in the bottom. Is there a step I am missing?

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    $\begingroup$ Solids can react, so if you design the titration appropriately, this will still work. $\endgroup$ – Zhe Feb 24 '17 at 16:05
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    $\begingroup$ In order to have the antacid neutralization reaction go fast add a known amount of excess acid and back titrate the extra acid with NaOH. $\endgroup$ – MaxW Feb 24 '17 at 16:43
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    $\begingroup$ Grind the solid well and stir or swirl as you titrate. $\endgroup$ – bpedit Feb 24 '17 at 16:48
  • $\begingroup$ So it doesn't matter if there is still solid in the solution? Just add acid until everything dissolves and then do the back-titration with NaOH? $\endgroup$ – Theodore Visvikis Feb 24 '17 at 19:54
  • $\begingroup$ That's what I would do, just like MaxW's comment. Good note by bpedit too; get that surface area up by grinding it until the consistency is as close to a "flour" as possible, then stir throughout dissolution and titration. $\endgroup$ – airhuff Feb 24 '17 at 20:14

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