# What is reaction between isopropyl alcohol and acetone?

What would be the probable reaction between acetone, $\ce{(CH3)2CO}$, and isopropyl alcohol, $\ce{CH3CHOHCH3}$, at room temperature without any catalyst in different concentrations?

• There would be none. – Ivan Neretin Sep 30 '16 at 5:42
• Sounds like a recipe for a MPV reduction except that there is no substrate and no catalyst.. – orthocresol Sep 30 '16 at 6:41
• @orthocresol, yes but with some metal catalyst I guess. – Khaliddhali Sep 30 '16 at 6:59
• As Ivan already said there would be no reaction. You might as well have any ketone with any alcohol - the only thing that could conceivably happen would be hemiacetal/acetal formation but that certainly needs acid catalysis. – orthocresol Sep 30 '16 at 7:02
• Unless you excite the acetone (UV irradiation), I'd suppose that nothing happens. – Klaus-Dieter Warzecha Sep 30 '16 at 16:52

I've used acetone/ipa mix to flush chromatography columns. There is no reaction between them without another reagent present

I mix rubbing alcohol and acetone together to clean flux off of stained glass that I have soldered. Nothing happens when you mix them.

Obviously these liquids do not react with each other. But they can be interconverted. Isopropanol can be converted to acetone simply by heating over a copper catalyst (https://en.wikipedia.org/wiki/Isopropyl_alcohol). And as many readers know, sodium borohydride or lithium aluminum hydride reduces acetone to isopropanol (https://www.chemguide.co.uk/organicprops/carbonyls/reduction.html).