Is there any research on how reported reaction times are distributed (in typical organic chemistry)?

I feel like I remember that there was a paper/talk discussing this, finding that there was a steep drop around 10-14 h (since one would then have to setup the reaction very late or come in very early for workup - to avoid staying in the lab in the midst of the night), but right now I cannot find anything on the topic.


closed as off-topic by bon, DavePhD, orthocresol, Geoff Hutchison, Todd Minehardt Sep 9 '16 at 15:50

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    $\begingroup$ 16 hours probably means "I set it up before leaving and found that it was done when I came back the next morning.", doesn't it? ;) $\endgroup$ – orthocresol Sep 7 '16 at 14:51
  • $\begingroup$ I guess so! I remember a total synthesis a few years ago, where one of the steps would have 200+ hours... Probably setup before going on vacation for Christmas/New Year's ;) $\endgroup$ – snurden Sep 7 '16 at 19:03
  • $\begingroup$ Also, another view is that if it isn't done overnight, the reaction does not work. Your question needs a better specification. $\endgroup$ – Lighthart Sep 7 '16 at 21:06
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    $\begingroup$ I'm voting to close this question as off-topic because it isn't really about a chemistry concept. It's really asking about studies on the behaviour of organic chemists. $\endgroup$ – bon Sep 9 '16 at 10:57
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    $\begingroup$ A professor in Munich once said: ‘There are only three reaction times. 5 minutes, i.e. you set it up and then you work it up; 2 hours, i.e. over lunch break and 16 hours i.e. over night.’ However, his analysis is skewed: It forgot 70 hours (over the week-end). $\endgroup$ – Jan Sep 9 '16 at 22:44

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