# Use of water in IR spectroscopy

I am familiar with the process of IR spectroscopy and the preparation of IR samples.

However, I am curious as to why you cannot use hygroscopic or protic solvents for IR spectroscopy. Is it just because it dissolves the cell (KBr/NaCl), or does it give an OH peak, or are there other reasons?

And are there any protocols that allow you to use water as a solvent for obtaining an IR spectrum?

Its a continual problem. Usually its due interfering absorptions (often total absorption) from water so try using D$_2$O instead, the frequency shift may be enough for you to be able to use it. Also change to using ATR (if possible), we use this in the teaching lab for several experiments on liquid samples without the need for any cell. Signal to noise is not so good though. You can also try subtraction via a water only spectrum against water plus sample. It will be messy but better than so data at all.