I have a large collection of structures (>10,000) that I've gathered from literature searches and I would like to find out which of those can be obtained from vendors. I know that eMolecules and ChemSpider provide such information, but getting that information for 10,000 structures in daunting.
On eMolecules, I can load a list of SMILES, search the databases, and download the results. The download process is not very robust, though, and I have to reconstitute a lot of pieces of information.
ChemSpider provides additional information regarding vendors, and I've tried using the ChemSpiPy API, but I consistently get an error from the ChemSpider server. Obviously something has changed with respect to the server that the API doesn't account for.
Are there other suggestions for where/how I might gather such vendor details for a very large collection of structures?