# Separating iron from blood

How can I separate iron from blood, without doing any damage to the blood/haemoglobin?

I have thought about using a magnet, but apparently iron in blood is not magnetic, and I have also looked at filtration techniques but not sure if that will affect the haemoglobin.

Updated Dec 2017: Let me add some context, I was/am looking for an alternative for chelation therapy such as Desferaloxamine infusions to remove iron in patients with iron overload as a result of repeated transfusions due to anemia

• I vaguely recall some work several years ago from several universities using magnetic nanoparticles coated with something that would bind to the haemoglobin. Outside of the body, they had an apparatus that would inject the nanoparticles, and then magnetically separate them out before putting the blood back in the body. Once separated, the nanoparticles would be treated (can't remember how) to release the haemoglobin. – Jon Custer Feb 15 '16 at 16:26
• Once the iron is removed, it's no longer Heme b, but protoporphyrin IX. – Klaus-Dieter Warzecha Feb 15 '16 at 16:37
• According to this study dtic.mil/dtic/tr/fulltext/u2/a266503.pdf , Iron can somehow be released from hemoglobin. I didn't fully understand it as I'm just a student myself, but hopefully it can help you out :) – N A Feb 15 '16 at 17:04
• This seems like an impossible task. The iron in blood is primarily in the hemoglobin itself, isn't it? So at the very least you are going to have to remove the iron from its heme ligand in hemoglobin, from iron-sulfur clusters in various enzymes in red and white blood cells, and from ferritin proteins, etc. – Curt F. Feb 16 '16 at 5:45
• There was a question from a casual chemistry textbook which is somewhat related. "A legend says that one fine young man gave his beloved an engagement ring made of iron. But that iron was not the trivial one: the young man obtained it out of his own blood. Calculate amount of blood required for a young man to produce $\pu{2.50 g}$ iron. The content of hemoglobin in the blood of an average young men is $\pu{150 g/dm3}$. The molar mass of human hemoglobin is $\pu{68800 g/mol}$. One hemoglobin molecule contains 4 iron atoms." Too bad there is no info how the young man did the tricky part:) – andselisk Aug 26 '17 at 6:50