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I am interested in the Biological Half Life of substances. In the previous wikipedia link, I've already found the half lives of common pharmaceutical products. I can't seem to find similar data for recreational substances, does anyone know these half lives?

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  • $\begingroup$ Sorry, didn't realise there was a biology beta. Does a pharmacology questions belong there? I don't know, flagged it. $\endgroup$ – Nathan Cooper Mar 26 '13 at 16:17
  • $\begingroup$ I think it would need some elaboration to be worthy of migrating, to be honest. I think as it is, it's okay here, but asking about specific classes of drugs would make it more scientific and rigorous. $\endgroup$ – jonsca Mar 27 '13 at 3:45
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Wikipedia reports biological half-lives for several recreational drugs I just tried (cocaine, THC, MDMA). In each case, I went to the page for the particular substance, and Wikipedia keeps an information box at the top of the article containing the pharmacokinetic data. THC's half-life has a citation to the scientific literature, while the other two I checked do not. I think it might be slightly harder in general to get good data for the purely recreational drugs. I would expect drugs without an accepted medical benefit to be less well-studied. To find what's there, though, it looks like you will be able to look up each active ingrediate individually. Depending on what you need, Wikipedia might be okay. If it's not, follow the Wikipedia citation back to the literature if it's there, or try PubMed.

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Try DrugBank. It's a comprehensive and free-to-use database for a large number of drugs. I saw it has data on Cocaine and Heroin (look in the pharmacology section).

(Yes, this question is three and a half years old, but it still may help someone...)

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  • $\begingroup$ What is the maximum number of atoms in a DrugBank molecule? [Your answer is "three and a half years old" now ;) ] $\endgroup$ – Blade Jun 11 '20 at 14:40
  • $\begingroup$ Not sure I understand what you mean... $\endgroup$ – Don_S Jun 11 '20 at 19:00
  • $\begingroup$ You suggest using DrugBank. Most datasets provide information on the number and type of atoms (e.g, QM9 dataset is consist of 134000 molecules made of C,O,N,F and H with maximum 9 atoms in a molecule). Was wondering if you have those info and can add them to the answer. $\endgroup$ – Blade Jun 11 '20 at 19:15
  • $\begingroup$ Ok, well, I don't have that info, but even if I had it, I do not understand how it would be related to the original question. $\endgroup$ – Don_S Jun 11 '20 at 19:17
  • $\begingroup$ Nvm. Thank you. $\endgroup$ – Blade Jun 11 '20 at 19:22

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