Using WinCoot or SWISS PDB viewer, how would one merge monomeric structures that should be in dimer formation?
What I have done:
- I have downloaded the PDB-file which shows the monomer with a bound drug (Infliximab Fab fragments), but it should be a trimetric structure as whole -although you only get the monomer when you download the file (TNFa) .
- I have opened the file in both coot and SWISS-PDB viewer, and opened three copies of the monomer, but they just overlap and I am not able to combine them to the proper structure
I also know that it is possible to download the "biological assembly" PDB-file that has the entire trimetric structure, but the point here is to be able to do that on my own (which should be easy for those who know it?).
I am very new to all of this modeling, so there might be something basic I don’t understand. But I though that you can somehow "merge" the monomers by using some "layer" function? I am really unsure.