# History of octanol-water partition coefficient

We are aware that one of the basic information about a material is the logP value it has. The logP is worked out from the partitioning between the octanol and the water phases. Does anyone know who was the first to introduce this octanol-water partition coefficient? I had a look through the literature but was not able to find the author of that rule.

• Solid-state-chemistry? Really?? – bon Sep 21 '15 at 14:32
• well, no relevant tags available (the ones I thought of at least). I tried to add some myself, but my reputation is still very low to do so. Thanks for the new tags :) – Error404 Sep 21 '15 at 15:00
• I didn't create any new tags, I only added existing ones which you could have done yourself. – bon Sep 21 '15 at 16:25

Note bene: In the last article I've linked, mention is made that the phenomena was first investigated by Bertholet in 1872 and "put on a firm basis by Nernst in 1891." That said, the 1971 publication of Leo $\it{et\; al}$ is the first modern/comprehensive listing of octanol-water partition coefficients and the place where the symbology (and definition) were written.