Why is this reaction successful: enter image description here

Why doesn't metal-halide exchange occur easily to get Ar-MgCl and R-Br?

  • $\begingroup$ Why do you think it should? Could you elaborate? $\endgroup$ – Mithoron Jul 29 '15 at 20:24
  • $\begingroup$ A similar reaction is used in the synthesis of sibutramine, only the aldehyde is replaced with a cyanide group, and R=isobutyl. $\endgroup$ – RBW Jul 30 '15 at 8:55
  • $\begingroup$ I guess the reason is that metal halide exchange is very fast only in the case of lithium organyls while it proceeds slower for grignard reagents. $\endgroup$ – logical x 2 Oct 17 '16 at 10:02
  • $\begingroup$ And I guess that chlorine isn't that susceptible, while Br and I would be. $\endgroup$ – RBW Oct 17 '16 at 12:31

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