How do we number the carbon atoms in symmetrical molecules while giving R and S notation. For instance, in 2,3-Dibromobutane, there is an ambiguity over which is carbon C2 and carbon C3. Will we call it (2R,3S) or (2S,3R)?
The current version of Nomenclature of Organic Chemistry – IUPAC Recommendations and Preferred Names 2013 (Blue Book) reads as follows:
P-14.4 NUMBERING
When several structural features appear in cyclic and acyclic compounds, low locants are assigned to them in the following decreasing order of seniority:
(…)
(j) When there is a choice for lower locants related to the presence of stereogenic centers or stereoisomers, the lower locant is assigned to CIP stereodescriptors Z, R, M, and r (pseudoasymmetry) that are preferred to E, S, P, and s, respectively, which are preferred to the non-CIP stereodescriptors cis, trans, or r (reference), c, and t (…).
(…)
Therefore, the chirality center R receives the lowest locant and thus a systematic name is (2R,3S)-2,3-dibromobutane and not (2S,3R)‑2,3‑dibromobutane.
However, your drawing shows (2R,3R)-2,3-dibromobutane.