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how should we use di-tert-butyl dicarbonate(diBOc) as solvent?
In reference, diBOc was in the form of a liquid but when I checked the bottle it was in solid state.
diBOc should be stored at 8-10 ℃. So how is it possible for it to be used as liquid?
Is it OK to melt it at RT? Wouldn't melting, make diBOc have structural differences?
Di-tert-butyl dicarbonate melts around room temperature (m.p.=23°C). It does not decompose at this or even slightly higher temperatures. For example, it is typically purified by distillation under reduced pressure at temperatures up to around 65°C. At higher temperatures it will decompose to isobutene, t-butyl alcohol and carbon dioxide.
In any case it is OK to melt di-tert-butyl dicarbonate and use it between room temperature and up to around 40-60°C. Just make sure that when you open the bottle and use it that you do so in a dry environment as water will decompose di-tert-butyl dicarbonate.
