A couple of reactions of glucose have been a source of great confusion to me. One of them is it's reaction with the Brady's reagent. It's pretty debatable whether the result is positive or negative. Could someone please shed some conclusive light onto this?
Furthermore, Glucose itself successfully produces an oxime with hydroxylamine. In contrast, it's pentaacetate fails to do so. Why does this occur? Why can't the pentaacetate, like glucose, "break out" of it's cyclic form to give a positive hydroxylamine test?
Edit: I found out about the oxime test, I had overlooked the fact that glucose pentaacetate doesn't have any hemiacetal. The Brady's test though, is still open for debate.