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As described in a paper, the authors removed the hexane from the nBuLi solution "under reduced pressure". I was wondering if anyone had any experience on how to proceed safely with this procedure. I was also wondering if anyone could confirm to me that nBuLi not in hexane and under vacuum is indeed stable.

Flower, K. R.; McGown, A. T.; Miles, P. J.; Pritchard, R. G.; Warren, J. E. Isolation of $\ce{1,4-Li2-C6H4}$ and Its Reaction with $\ce{[(Ph3P)AuCl]}$. Dalton Trans. 2010, 39 , 3509. https://doi.org/10.1039/b925355f.

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    $\begingroup$ Once upon a time solid butyllithium was commercially available, so yes it is stable if air and moisture are rigourously excluded $\endgroup$
    – Waylander
    Commented Jan 29 at 7:47
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    $\begingroup$ You state only a part of the story. But once hexane is removed under reduced pressure (Schlenk line?), what do you want to do? Maybe the swap of solvents (just a guess) is not necessary as nBuLi equally is commercially available as a solution in diethyl ether, THF, etc. And of course, the scale of the intended operation (both volume and initial concentration of the solution to «process» -- 10 mL 2M in hexanes is easier to manage than the 11 M stock). $\endgroup$
    – Buttonwood
    Commented Jan 29 at 11:25
  • $\begingroup$ Thanks! @Buttonwood This question was more out of curiosity on how the authors of the paper managed to remove the hexane from the nBuLi/Hexane solution without it catching on fire. From the other answer it seems possible they dried it on the schlenk line. $\endgroup$
    – The Red Man Jolan Bonelli
    Commented Feb 15 at 2:19

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