I am looking to achieve isotope separation using transition states.
In the rxn of dienes with halogens, based on the temperature, the dienes can create a thermodynamic product or a kinetic product. The kinetic product is reversible, while the thermodynamic product is not. This is because thermodynamic products have a higher energy need for transition states.
In the context of transition states, I see some possibility of having two different products, each having one type of isotope, by selectively exciting one isotope while leaving the other isotopes untouched.
I look to achieve this by the following protocol:
- Dissolve the isotopes in some liquid.
- Put the liquid-isotope solution in NMR machine.
- Make NMR machine "tip over" only one variety of isotope repeatedly to gain thermal energy.
- Maintain temperature of liquid so that other isotopes not tipped over can only maintain the kinetic product.
- Make NMR machine energize target isotope enough so that it can produce thermodynamic product.
- Put in the diene to react with isotopes.
- Seperate the now permanent thermodynamic product, with some pre-existing method to separate isomers.
- Yield the target isotope.
Is this method viable? I am proposing this method with the assumption that thermodynamic and kinetic products can be produced based on the individual energies of halogens, which I am not entirely sure of.
In addition, would this mechanism be viable for reactants other than halogens (using a different TS and rxn, of course)? I am interested in enriching heavier metals, such as uranium (where conveniently, 235 reacts with NMR while 238 does not).