I need to take the sodium nucleotide salts I have available in my lab and modify them to instead contain some more exotic counterions. Can I do this by binding my nucleotides to a strong anion exchange resin, washing, and eluting with a salt of my preferred counter ion? Seems like it should work, but Im a biologist, not a chemist. Any other suggestions would also be appreciated! Thanks very much!

  • 3
    $\begingroup$ Ion-exchange chromatography is typically used to achieve that. This is how ionic liquids get their different "exotic" anions. $\endgroup$
    – AChem
    Jan 9 at 20:53


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