I'm interested in the acid-base properties of a metabolite, biotinyl 5' AMP in the cell. Biotinyl-5'-AMP can react with protein lysine side chains at the anhydride linkage to form biotinyl-lysine. This immediate reaction is not, however, the focus of this question. I'm struggling to understand for sure whether, in its soluble state, biotinyl-5'-AMP is likely to adsorb or donate (further) protons to its immediate chemical neighbours in the cell, particularly weak bases or acids.
How can I intuitively understand the acid-base properties of an organic molecule in solution with multiple functional groups? Biotinyl-5'-AMP is deprotonated in solution, as far as I am aware. Would this deprotonated species then have further ability to donate or adsorb protons? I have found database information about this molecule suggesting the pKa of the strongest acid and strongest basic groups (0.83 and 4.99 respectively), and a line that the molecule is likely to be a 'strong basic compound'.
Given those database figures and the structure/functional groups (figure below): How can I intuitively understand the acid-base properties of this compound in solution? How should I interpret and rationalise those database pKa values? How should I then predict the propensity of biotinyl-5'-AMP to influence the pKa of immediately-adjacent weak acids and bases in the cell?