In the presence of isolated ketones, can organocuprates add to secondary tosylates in an SN2 fashion without adding to the ketones?
Cuprates (also known as Gilman reagents) do not generally react with isolated ketones. If they did the widely used reaction of cuprates with alpha/beta unsaturated ketone would not work to give the substituted ketone product.
According to this review alkyl cuprates do react with secondary tosylates to give the expected SN2 product. I have not, however, been able to find an example of this being done in the presence of an isolated ketone