# How can I filtrate Pd2(dba)3 and P(o-tol)3? (Celite filtration failed)

I am conducting an organic synthesis involving Stille coupling, using $$\ce{Pd2(dba)3}$$ and $$\ce{P(o-tol)3}$$ as catalysts. Reaction solvent is toluene in which the catalysts also dissolve. Many texts said that celite pad can filtrate these catalysts, but I failed. I tried vacuum filtration using buchner filter, and poured $$\pu{0.0087 g}$$ $$\ce{Pd2(dba)3}$$ in $$\approx \pu{25 mL}$$ toluene. $$\ce{Pd2(dba)3}$$ in toluene has dark red color, but filtrate also has same color. TLC spot was also in same position. Is there any other way than column chromatography?

• Filtration is not going to remove the phosphine, or the phosphine oxide which is also likely to be present as they are both toluene soluble. You are going to have to run chromatography. Jun 21 '21 at 6:46
• Thank you for advice. Does filtration work for Pd catalyst? I saw many papers using Pd catalyst employ Celite filtration. (although I failed) Jun 21 '21 at 6:59
• Celite filtration only removes fine solids, so may take out degraded catalyst. You still have to run chromatography to get rid of tin residues. Jun 21 '21 at 7:21