With the use of Lewis acid Aluminium Trichloride, which one would have a stronger nucleophilicity? Silyl Ketene Acetal (CAS: 31469-15-5) or a phenyl group?


Reacting with what electrophile?

In general the silyl ketene acetal will be more reactive, after all the Mukaiyama reaction can be run in Toluene Mukaiyama Reaction wikipedia page

  • $\begingroup$ α,β-unsaturated carbonyl. yeah I think SKA will be more reactive. Thank you for sharing. $\endgroup$
    – chemrese
    May 6 at 11:04
  • 1
    $\begingroup$ If you are happy with the answer please accept it $\endgroup$
    – Waylander
    May 6 at 11:16

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