# Are protons or electrons responsible for the chemistry of an atom? [closed]

Is the question in a correct form? I can't add anything as a comment.

As an illustration, you can take helium $$(\ce{He})$$ and a hydride ion $$(\ce{H-}).$$ Both have 2 electrons on an 1s, however the $$\ce{He}$$ is neutral, while the nucleus of $$\ce{H}$$ is compensating only for one charge. This result in totally different energy levels and stability, different affinity for oxidation or other chemical reactions.