In the second episode of The Association for Mass Spectrometry & Advances in the Clinical Lab (MSACL) podcast, namely Getting going with mass spectrometry : Josh learns chromatography (aired 2021-01-07), Dr. Russell Grant mentioned the following tip at 01:03:11 (I apologize in advance for any inaccuracies in the transcript):
The other thing that is often forgotten there is that you can drop the capillary voltage to zero. It's not as good as the diverter valve, but you are not going to be pulling the stuff towards the mass-spectrometer. If you only have a couple of windows and a bunch of junk, you can just keep capillary voltage on during these desired windows and save your diverter valves' maintenance time because they can become maintenance-limiting.
I would think it would lead to a more frequent cleaning of the ionization chamber. Is the gain in postponed maintenance of a diverter valve really worth it?
Are there any other use cases when disabling capillary voltage could be a superior alternative to using a diverter valve?