I’m interested in quantitating lithium via NMR using a Magritek Spinsolve 60MHz bench top NMR spectrometer. Is there any evidence that suggests the volume of the liquid sample used in the NMR tube has any effect on the area of the spectra peaks? I’m interested in hearing opinions on the matter before running tests verifying if such correlations in-fact do exist.
I’ve seen in relevant literature that 0.6-1mL is generally a sufficient amount of solution for the 5mm tubes. However it’s not clear to me yet if this volume should be consistent between the calibrants and experimental solutions for analytical NMR. Thanks!