I remember my teacher saying that during E2 (elimination bimolecular) reactions of alkanes, if the strong base that is used as a reagent is a bulky one, it has higher probability of giving a Hofmann (less stable) product as the major product even if there are possibilities for a Saytzeff (or Zaitsev) product to form.
How should I find if a base is bulky or not?
Some bases like t-butoxide ion are pretty obvious. I usually just guess it is based on how much steric-clouded it seems when I draw a representation on a paper. Is there any better way to figure this out?