What could be the meaning of the red circles with letters S in them in the diagram below? I searched in the text but could not find.
From "Role of TREK-1 in Health and Disease, Focus on the Central Nervous System", Figure 2:
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Sign up to join this communityWhat could be the meaning of the red circles with letters S in them in the diagram below? I searched in the text but could not find.
From "Role of TREK-1 in Health and Disease, Focus on the Central Nervous System", Figure 2:
It almost certainly refers to the amino acid (residue) serine. The numbers (300, 333, 351) refer to the residue numbers. The COOH at the end signifies the C-terminus of the protein (subunit).
The black P's next to it are phosphate groups; both protein kinase A and C ("PKA" and "PKC") are involved in control of protein activity precisely via phosphorylation of serine residues in proteins (amongst others).