# Synthesis cost of Fomepizole

Fomepizole is essential drug for methanol poisoning, I observed it cost too much like in 1000's of dollar for couple of ml. Is cost due to patents, or due to synthesis cost,structure of molecule looks very small and easy, then why so much difficulty in synthesizing molecule ?

• It's not a matter of synthesis, so it seems borderline off-topic as it's about economics of pharmacy. – Mithoron Sep 29 '20 at 21:27
• its also about synthesis cost with purity enough for human use also. If someone make clear that it is relatively cheap to get high purity product, i guess one will get it in black market – murmansk Sep 29 '20 at 21:46

Interesting that the cost in the US for the USDA-approved form is US$900 per 1.5 ml IV ampule. (Specific gravity is given as ~1, i.e. 1.5 g per ampule). That chemical, 4-methylpyrazole, "For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.", is available for US$74 per g .