I am a home-chemist and I love dyes. I recently got my hands on sodium salt of erythrosine (tetra-iodinated fluorescein). I want to convert erythrosine to fluorescein. I speculate that using dilute NaOH solution might cause formation of sodium iodide and tetra-hydroxylated fluorescein. How can I reduce the alcohol groups without affecting the carboxylic acid groups.

Is there any better way to convert erythrosine to fluorescein?

Erythrosine Fluorescein

  • $\begingroup$ Would Sodium borohydride work? $\endgroup$ Jul 7, 2020 at 15:39
  • $\begingroup$ @Safrad Faisal Most probably, sodium borohydride will reduce the carboxylic groups. $\endgroup$
    – Anonymous
    Jul 8, 2020 at 10:43


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