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On C-nitrosation of ketones we get oximes. After this, the oxime formed is hydrolyzed ($\ce{H3O+}$ is added). What will be formed in the end? Does it follow Beckmann rearrangement or what?


1 Answer 1


Hydrolysis of the ketone oxime gives the 1,2-diketone as reported in this Synlett reference:

Treatment of alpha-methylene ketones with excess sodium nitrite and aqueous HCl in THF at reduced temperature provieds an effective tool for the preparation of a variety of 1,2-diketones


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