![6,6'-bis(hydroxymethyl)[1,1'-biphenyl]-2,2'-dicarboxylic acid](https://i.stack.imgur.com/GX2eo.jpg)
I was wondering that at optimum temperature can 6,6'-bis(hydroxymethyl)[1,1'-biphenyl]-2,2'-dicarboxylic acid show esterification reaction.
I know that the two phenyl groups aren't in the same plane so is esterification reaction still possible?
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1$\begingroup$ What conditions do you intend to use for the esterification? Acid catalysed or with a coupling agent? $\endgroup$– WaylanderApr 12 '20 at 9:20
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$\begingroup$ There's a base present ie NaOH and the temperature is of 100°C $\endgroup$– PSN03Apr 12 '20 at 9:33
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2$\begingroup$ You are not going to get esterification with NaOH present! $\endgroup$– WaylanderApr 12 '20 at 11:01
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these type of things are possible,
esterification is possible, check the reference.
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$\begingroup$ Can the carboxylic acid and alcohol react to give an ester at 100°C of temperature?? $\endgroup$– PSN03Apr 12 '20 at 9:35
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$\begingroup$ is this for research purpose ? or just exercise? $\endgroup$– HutchApr 12 '20 at 9:56
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$\begingroup$ It's for my knowledge and a part of my excercise $\endgroup$– PSN03Apr 12 '20 at 10:12